Delta Patcher is a GUI software that is able to create and apply xdelta patches as the ones supported by the xdelta tool developed by Joshua McDonald.
Delta Patcher is fully self-contained and does not depend on the xdelta3 tool at all. It’s written in C++ using wxWidgets for the GUI components and all the needed libraries are statically linked to the executable (except for GTK for Linux builds).
Relevant link: https://github.com/marco-calautti/DeltaPatcher
File download: